The science, with context
Research you can read for yourself.
Supplement research is useful when the details stay attached to the headline. This library connects the ingredients in our range with selected human studies and independent NIH resources. The studies below did not test finished Mitosupps products, and their authors do not endorse our store.
How to read a supplement study
Start with four questions: What ingredient and dose were tested? Who took it? How long did the study last? What actually changed?
A randomized trial compares groups to help separate an ingredient’s effect from other influences. A placebo gives that comparison a useful baseline. Small studies can identify promising findings, but their results need confirmation. A change in a blood test or another laboratory measurement does not necessarily mean a person feels better or has a lower risk of illness.
Also check whether the ingredient form and amount match your product. Results in older adults or people with a particular medical condition may not apply to a healthy person in their thirties. A nutrient can have an essential role in the body without extra supplementation providing an added benefit to someone who already gets enough.
Hyper D-3 + MK-7
Established role: Vitamin D helps the body absorb calcium, while vitamin K is involved in proteins that support normal bone physiology. That does not mean every adult needs a high-dose supplement.
Vitamin K2 and bone measurements
A three-year randomized trial studied 180 mcg of MK-7 daily in 244 postmenopausal women. It found less decline in some bone measurements. The population matters: this result does not establish the same effect in younger women or men.
Keep dose in perspective: Our listed vitamin D3 strength is 5,000 IU per capsule. The NIH adult daily upper intake level is 4,000 IU from all sources. Discuss this strength with a qualified healthcare professional; do not assume that more is better.
NIH: vitamin D functions, intake limits and interactions · NIH: vitamin K and medication interactions
PQQ Energy
What researchers are exploring: PQQ has been studied for cognitive-test performance. B12, acetyl-L-carnitine and CoQ10 have their own roles and evidence; a study of one ingredient does not establish the effect of their combination.
A 12-week PQQ trial
A placebo-controlled study in adults aged 20–65 tested 20 mg of PQQ disodium salt daily and reported improvement in selected cognitive scores. It was a small, short-term study with manufacturer-affiliated authors. It did not establish a guaranteed improvement in everyday focus, energy or long-term brain health.
A useful B12 distinction: B12 is necessary for normal metabolism and nervous-system function. Extra B12 has not shown performance or endurance benefits when a person’s B12 status is already sufficient.
NIH: B12, nutritional needs and energy claims · NIH: carnitine evidence and safety
Ubiquinol (Q-10)
Ingredient context: Ubiquinol is the reduced form of CoQ10, a compound involved in cellular energy processes. That biological role is different from a demonstrated benefit of taking extra CoQ10.
Blood CoQ10 and vascular-function markers
An eight-week randomized trial assigned 51 adults with elevated cholesterol and impaired endothelial function to 100 mg, 200 mg or placebo. Ubiquinol increased blood CoQ10 and improved a measurement of blood-vessel function. The study was small and assessed markers; it did not establish fewer heart attacks or a noticeable energy boost.
The trial did not test our 220 mg product. A similar amount does not make a different formulation clinically equivalent.
Read the ubiquinol trial on PubMed · NCCIH: CoQ10 evidence and interactions
Glutathione
Mixed findings deserve space: Glutathione is part of the body’s antioxidant systems. Human trials of oral supplementation have not all produced the same results.
Two trials, different outcomes
A six-month trial in 54 adults tested 250 or 1,000 mg per day and found increases in several measurements of glutathione. A four-week trial in 40 adults tested 500 mg twice daily and did not find significant changes in its measured glutathione or oxidative-stress markers.
These studies differed in duration and dose. Neither tested our 500 mg combination with milk thistle and alpha-lipoic acid. The findings do not establish a detoxification, disease-prevention or skin-whitening benefit.
Read the six-month trial · Read the four-week trial
Milk thistle has also been researched, but the NIH describes the evidence for health conditions as limited or conflicting. Its presence in a formula does not establish liver protection.
Collagen + Vitamin C
An established nutrient function: Vitamin C is needed for normal collagen production. Studies of supplemental collagen peptides and hyaluronan ask a different question: whether particular amounts change measured skin characteristics.
Collagen peptides and skin elasticity
An eight-week trial in 69 women aged 35–55 studied 2.5 or 5 g of specific collagen peptides per day and reported improvements in skin elasticity. Our formula provides 0.8 g per two-capsule serving. Its amount and peptide specification differ, so the study should not be read as a promise of equivalent results.
Read the collagen trial on PubMed
Oral hyaluronan
A small 12-week trial studied 120 mg daily of specified hyaluronan ingredients and reported changes in selected wrinkle measures. It included supplier-affiliated authors. Our formula provides 100 mg per serving; different amounts and molecular weights may behave differently.
Read the hyaluronan trial on PubMed · NIH: vitamin C functions and safety
Put the evidence in your own context.
This is a selected reading library, not an exhaustive review or individual medical advice. Consider your diet, existing supplements, medications and health history with a qualified healthcare professional. Supplements are not a substitute for medical evaluation or treatment.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.